Stem cell therapy: an emerging modality in glomerular diseases
Umang Thakkar - Collection Omn.univ.europ.
52 pages, parution le 10/05/2017
Résumé
In the human body kidney is one special organ which is highly terminally differentiated and has very limited capacity to regenerate following injury/ insult. Hence once glomerular diseases set in, they usually progress to end-stage renal disease (ESRD) requiring dialysis or renal transplantation (RT) for better quality of life. However shortage of implantable kidneys and complications of transplantation like immune rejection immunosuppression related morbidity/ mortality, including immunocompromised status, metabolic disorders, infections and malignancies, RT remains a challenge. Therapeutic options available for management of glomerular diseases include symptomatic treatment strategies to delay progression to ESRD. Stem cell-based therapy (SCT) forms recent innovative therapeutic modalities for such diseases due to its ability to inhibit inflammation, replenish dying tissues/ cells and promote regeneration. This review focuses on SCT for treatment of glomerular diseases, including various cell sources used and recent advances in preclinical and clinical studies.
Caractéristiques techniques
| PAPIER | |
| Éditeur(s) | Editions universitaires européennes |
| Auteur(s) | Umang Thakkar |
| Collection | Omn.univ.europ. |
| Parution | 10/05/2017 |
| Nb. de pages | 52 |
| Format | 15.2 x 22.9 |
| Couverture | Broché |
| Poids | 92g |
| EAN13 | 9783330869264 |
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